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This episode is a recording of the 06/16/2016 Facebook Live event, "Ask Chris Masterjohn, PhD Anything About Heart Disease." Among the questions answered in this episode are the following: Should we be micromanaging specific saturated fatty acids to prevent heart disease? Should we use our knowledge of our ApoE genotype to help decide what to eat (and specifically, should the E4 allele causes us to avoid saturated fat)? The persistent importance of the total-to-HDL-cholesterol ratio. Why the vitamin E content of HDL particles could be determining its protective functions. Can established heart disease be reversed? Does moderately high blood pressure directly contribute to heart disease, or is the association between moderately high blood pressure and heart disease reflect some underlying factor that contributes to both? Do Americans consume too much calcium? Using essential oils to combat heart disease. How do we approach the question of using diet and lifestyle versus medication?