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Fact check: Is the Botox chemical really the deadliest chemical in the world. Botulinum toxin, one of the most poisonous biological substances known, is a neurotoxin produced by the bacterium Clostridium botulinum. Injections with botulinum toxin are generally well tolerated and there are few side effects. Some unwanted effects can include: Mild pain, local edema (fluid buildup) and/or erythema (reddening of the skin) at the injection site, Numbness, Headache, allergic reactions, rash, itching, asthma, red welts, shortness of breath, diarrhea, stomach pain, loss of appetite, injection site reactions including bruising, bleeding, pain, redness, bleeding, swelling, or infection, Malaise - feeling generally unwell, Mild nausea, Temporary unwanted weakness/paralysis of nearby muscles or twitching, fever, cough, anxiety, fatigue, dry mouth, ringing in your ears, increased sweating in areas other than the underarms, urinary tract infections, burning/painful urination, difficulty urinating, sore throat, runny nose, flu symptoms, cold symptoms, respiratory infections, dizziness, drowsiness, faintness, Weakness, swelling or bruising of the lower eyelid or lateral rectus (a muscle controlling eye movement),